- Born: 1454
- Died: 1510
- Sons: Uesugi Norifusa (adopted; 1466-1524)
- Distinction: Lord of Kôzuke
- Japanese: 上杉顕定 (Uesugi Akisada)
Akisada was a son of Uesugi Fusasada. He fought the Ogigayatsu-Uesugi off and on for decades, allying with Ashikaga Shigeuji and conducting battles at Sanemakihara, Nanasawa, Sugaya, and elsewhere. He then became distracted by the independent aspirations of Nagao Tamekage of Echigo province and was killed in an attempt to bring him in line.
- Initial text from Sengoku Biographical Dictionary (Samurai-Archives.com) FWSeal & CEWest, 2005