- Born: 1603
- Died: 1661
- Sons: Matsudaira Yorishige (1622-1695), Tokugawa Mitsukuni (1628-1670)
- Titles: Saemon no kami
- Japanese: 徳川頼房 (Tokugawa Yorifusa)
His mother was Oman no Kata. He was given a 100,000 koku fief at Shimotzuma in Hitachi province as a child (1603), and in 1621 was transferred to Mito han, worth 350,000 koku. As a young man he was tutored by Nakayama Bizen no kami Nobuyoshi (1576-1642), a member of a former Hôjô retainer family. Yorifusa is sometimes said to have been considered the most clever of Ieyasu's last three sons, and a number of anecdotes involving the three of them and Ieyasu survive. Yorifusa's Mito domain line became the third of the gosanke, a lineage which two centuries later provided the 15th and final Tokugawa shôgun, Tokugawa Yoshinobu.
- Initial text from Sengoku Biographical Dictionary (Samurai-Archives.com) FWSeal & CEWest, 2005