- Died: 1859
- Ranks and Titles: Hoi; posthumously Junior Fourth Rank
- Other Names: 佐藤 捨蔵 (Satô Sutezô)
- Japanese: 佐藤一斎 (Satô Issai)
Satô Issai was a Confucian scholar in the service of the Tokugawa shogunate and instructor at the Yushima Seidô Confucian school.
In 1853, he was one of a team of scholars and officials assigned to translate the diplomatic documents presented to the shogunate by Commodore Matthew Perry of the United States.
- Ishin Shiryô Kôyô 維新史料綱要, vol 1 (1937), 432, 503.; vol. 3, 220.