- Birth: 1555
- Death: 1627/4/25
- Other names: Kyuuemon, Hoda Yasumasa
- Title: Bizen no kami
- Sons: Sakuma Katsumune, Sakuma Katsumasa, Sakuma Katsuyuki
- Daughters: Wife of Kuwayama Kazunao, Wife of Hojo Ujinobu, Wife of Mori Takanari, Wife of Kurushima Michiharu, Wife of Shinjô Naruyoshi
Yasumasa was the son of Sakuma Moritsugu. He was initially adopted into the Hoda clan, and was known as Hoda Yasumasa. He served Shibata Katsuie, and after his death, served Oda Nobuo. After peace was struck between Nobuo and Toyotomi Hideyoshi, he served Hojo Ujiyasu. After the fall of Odawara castle, he served Gamô Ujisatô. It was at this point that he changed his name from Hoda back to Sakuma. After Gamo Ujisato's death, he served Tokugawa Ieyasu, and was given a 7,000 koku fief in Omi province. In 1615 he was granted a castle in Shinano province, with a value of 30,000 koku. His brothers were Sakuma Morimasa, Sakuma Katsumasa, and Sakuma Katsuyuki.