Ujishige was the eldest son of Hôjô Tsunashige. He was a capable commander and was well-liked by Hôjô Ujiyasu. He distinguished himself in battle against Uesugi Kenshin in 1561 and against Takeda Shingen in 1569. In the latter campaign, he defended Tamanawa castle in Sagami province stoutly. He died of natural causes in 1578 and his house was eventually inherited by Hôjô Ujikatsu.
- Initial text from Samurai-Archives.com FWSeal & CEWest, 2005